Trabectedin: A drug from the sea that strikes tumor-associated macrophages

Tumor-associated macrophages (TAMs) and other myeloid cells that infiltrate neoplastic lesions promote tumor progression and are associated with poor patient prognosis. We have recently demonstrated that trabectedin, a licensed and commercially available anticancer agent, is selectively cytotoxic fo...

Full description

Bibliographic Details
Main Authors: Allavena, Paola, Germano, Giovanni, Belgiovine, Cristina, D’Incalci, Maurizio, Mantovani, Alberto
Format: Online
Language:English
Published: Landes Bioscience 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716756/