IL-21 in cancer immunotherapy: At the right place at the right time
Interleukin-21 (IL-21) has been described as a potent stimulator of antitumor T-cell immunity, but also of autoimmune reactions and oncogenesis. Antigen presenting cells genetically modified to release IL-21 allow for the expansion of tumor-specific T cells exhibiting favorable effector and growth c...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Landes Bioscience
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716748/ |