Evaluating cell lines as tumour models by comparison of genomic profiles

Cancer cell lines are frequently used as in vitro tumour models. Recent molecular profiles of hundreds of cell lines from The Cancer Cell Line Encyclopedia and thousands of tumour samples from the Cancer Genome Atlas now allow a systematic genomic comparison of cell lines and tumours. Here we analys...

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Bibliographic Details
Main Authors: Domcke, Silvia, Sinha, Rileen, Levine, Douglas A., Sander, Chris, Schultz, Nikolaus
Format: Online
Language:English
Published: Nature Pub. Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715866/