H2O2-responsive molecularly engineered polymer nanoparticles as ischemia/reperfusion-targeted nanotherapeutic agents
The main culprit in the pathogenesis of ischemia/reperfusion (I/R) injury is the overproduction of reactive oxygen species (ROS). Hydrogen peroxide (H2O2), the most abundant form of ROS produced during I/R, causes inflammation, apoptosis and subsequent tissue damages. Here, we report H2O2-responsive...
Main Authors: | , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715762/ |