MicroRNA-200a Regulates Grb2 and Suppresses Differentiation of Mouse Embryonic Stem Cells into Endoderm and Mesoderm

MicroRNA-200a Regulates Grb2 and Suppresses Differentiation of Mouse Embryonic Stem Cells into Endoderm and Mesoderm

The mechanisms by which microRNAs (miRNAs) affect cell fate decisions remain poorly understood. Herein, we report that miR-200a can suppress the differentiation of mouse embryonic stem (ES) cells into endoderm and mesoderm. Interestingly, miR-200a directly targets growth factor receptor-bound protei...

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Bibliographic Details
Main Authors: Liu, Yang, Liu, Qidong, Jia, Wenwen, Chen, Jie, Wang, Jianmin, Ye, Dan, Guo, Xudong, Chen, Wen, Li, Guoping, Wang, Guiying, Deng, Anmei, Kang, Jiuhong
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715486/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715486/

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