T-Cell Mediated Immune Responses Induced in ret Transgenic Mouse Model of Malignant Melanoma

Poor response of human malignant melanoma to currently available treatments requires a development of innovative therapeutic strategies. Their evaluation should be based on animal models that resemble human melanoma with respect to genetics, histopathology and clinical features. Here we used a trans...

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Bibliographic Details
Main Authors: Abschuetz, Oliver, Osen, Wolfram, Frank, Kathrin, Kato, Masashi, Schadendorf, Dirk, Umansky, Viktor
Format: Online
Language:English
Published: MDPI 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712696/