Home Sweet Home: The Tumor Microenvironment as a Haven for Regulatory T Cells
CD4+Foxp3+ regulatory T cells (Tregs) have a fundamental role in maintaining immune balance by preventing autoreactivity and immune-mediated pathology. However this role of Tregs extends to suppression of anti-tumor immune responses and remains a major obstacle in the development of anti-cancer vacc...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Frontiers Media S.A.
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712544/ |