Home Sweet Home: The Tumor Microenvironment as a Haven for Regulatory T Cells

CD4+Foxp3+ regulatory T cells (Tregs) have a fundamental role in maintaining immune balance by preventing autoreactivity and immune-mediated pathology. However this role of Tregs extends to suppression of anti-tumor immune responses and remains a major obstacle in the development of anti-cancer vacc...

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Bibliographic Details
Main Authors: Ondondo, Beatrice, Jones, Emma, Godkin, Andrew, Gallimore, Awen
Format: Online
Language:English
Published: Frontiers Media S.A. 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712544/