Berberine Targets AP-2/hTERT, NF-κB/COX-2, HIF-1α/VEGF and Cytochrome-c/Caspase Signaling to Suppress Human Cancer Cell Growth

Berberine (BBR), an isoquinoline derivative alkaloid isolated from Chinese herbs, has a long history of uses for the treatment of multiple diseases, including cancers. However, the precise mechanisms of actions of BBR in human lung cancer cells remain unclear. In this study, we investigated the mole...

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Bibliographic Details
Main Authors: Fu, Lingyi, Chen, Wangbing, Guo, Wei, Wang, Jingshu, Tian, Yun, Shi, Dingbo, Zhang, Xiaohong, Qiu, Huijuan, Xiao, Xiangsheng, Kang, Tiebang, Huang, Wenlin, Wang, Shusen, Deng, Wuguo
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711861/