Control of DNA minor groove width and Fis protein binding by the purine 2-amino group

The width of the DNA minor groove varies with sequence and can be a major determinant of DNA shape recognition by proteins. For example, the minor groove within the center of the Fis–DNA complex narrows to about half the mean minor groove width of canonical B-form DNA to fit onto the protein surface...

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Bibliographic Details
Main Authors: Hancock, Stephen P., Ghane, Tahereh, Cascio, Duilio, Rohs, Remo, Di Felice, Rosa, Johnson, Reid C.
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711457/