The HCMV gH/gL/UL128-131 Complex Triggers the Specific Cellular Activation Required for Efficient Viral Internalization into Target Monocytes

The HCMV gH/gL/UL128-131 Complex Triggers the Specific Cellular Activation Required for Efficient Viral Internalization into Target Monocytes

We have established that HCMV acts as a specific ligand engaging and activating cellular integrins on monocytes. As a result, integrin signaling via Src activation leads to the functional activation of paxillin required for efficient viral entry and for the biological changes in monocytes needed for...

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Bibliographic Details
Main Authors: Nogalski, Maciej T., Chan, Gary C. T., Stevenson, Emily V., Collins-McMillen, Donna K., Yurochko, Andrew D.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708883/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708883/

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