Homeostatic control of Argonaute stability by microRNA availability
Homeostatic mechanisms regulate the abundance of many small RNA components. We used Drosophila and mammalian systems to demonstrate a conserved homeostatic system in which the status of miRNA biogenesis controls Argonaute protein stability. Clonal analyses of multiple mutants of core Drosophila miRN...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702675/ |