Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis

Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis

Exome sequencing has become a powerful and effective strategy for discovery of genes underlying Mendelian disorders1. However, use of exome sequencing to identify variants associated with complex traits has been more challenging, partly because the samples sizes needed for adequate power may be very...

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Bibliographic Details
Main Authors: Emond, Mary J, Louie, Tin, Emerson, Julia, Zhao, Wei, Mathias, Rasika A., Knowles, Michael R., Wright, Fred A., Rieder, Mark J., Tabor, Holly K., Nickerson, Debbie A., Barnes, Kathleen C., GO, Lung, Gibson, Ronald L., Bamshad, Michael J.
Format: Online
Language:English
Published: 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702264/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702264/

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