Selective copper(II) acetate and potassium iodide catalyzed oxidation of aminals to dihydroquinazoline and quinazolinone alkaloids

Copper(II) acetate/acetic acid/O2 and potassium iodide/tert-butylhydroperoxide systems are shown to affect the selective oxidation of ring-fused aminals to dihydroquinazolines and quinazolinones, respectively. These methods enable the facile preparation of a number of quinazoline alkaloid natural pr...

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Bibliographic Details
Main Authors: Richers, Matthew T, Zhao, Chenfei, Seidel, Daniel
Format: Online
Language:English
Published: Beilstein-Institut 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701376/