N-ras couples antigen receptor signaling to Eomesodermin and to functional CD8+ T cell memory but not to effector differentiation

N-ras couples antigen receptor signaling to Eomesodermin and to functional CD8+ T cell memory but not to effector differentiation

N-ras−/− CD8+ T cells have an intrinsic defect in Eomes expression resulting in impaired generation of protective memory cells that can be rescued by enforced Eomes expression.

Bibliographic Details
Main Authors: Iborra, Salvador, Ramos, Manuel, Arana, David M., Lázaro, Silvia, Aguilar, Francisco, Santos, Eugenio, López, Daniel, Fernández-Malavé, Edgar, Del Val, Margarita
Format: Online
Language:English
Published: The Rockefeller University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698526/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698526/

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