The First Korean Case of Sphingobacterium spiritivorum Bacteremia in a Patient with Acute Myeloid Leukemia

Sphingobacterium spiritivorum has been rarely isolated from clinical specimens of immunocompromised patients, and there have been no case reports of S. spiritivorum infection in Korea to our knowledge. We report a case of S. spiritivorum bacteremia in a 68-yr-old woman, who was diagnosed with acute...

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Main Authors:	Koh, Young Rae, Kim, Shine Young, Chang, Chulhun L, Shin, Ho-Jin, Kim, Kye-Hyung, Yi, Jongyoun
Format:	Online
Language:	English
Published:	The Korean Society for Laboratory Medicine 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698308/

id	pubmed-3698308
recordtype	oai_dc
spelling	pubmed-36983082013-07-03 The First Korean Case of Sphingobacterium spiritivorum Bacteremia in a Patient with Acute Myeloid Leukemia Koh, Young Rae Kim, Shine Young Chang, Chulhun L Shin, Ho-Jin Kim, Kye-Hyung Yi, Jongyoun Case Report Sphingobacterium spiritivorum has been rarely isolated from clinical specimens of immunocompromised patients, and there have been no case reports of S. spiritivorum infection in Korea to our knowledge. We report a case of S. spiritivorum bacteremia in a 68-yr-old woman, who was diagnosed with acute myeloid leukemia and subsequently received chemotherapy. One day after chemotherapy ended, her body temperature increased to 38.3℃. A gram-negative bacillus was isolated in aerobic blood cultures and identified as S. spiritivorum by an automated biochemical system. A 16S rRNA sequencing analysis confirmed that the isolate was S. spiritivorum. The patient received antibiotic therapy for 11 days but died of septic shock. This is the first reported case of human S. spiritivorum infection in Korea. Although human infection is rare, S. spiritivorum can be a fatal opportunistic pathogen in immunocompromised patients. The Korean Society for Laboratory Medicine 2013-07 2013-06-24 /pmc/articles/PMC3698308/ /pubmed/23826566 http://dx.doi.org/10.3343/alm.2013.33.4.283 Text en © The Korean Society for Laboratory Medicine. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Koh, Young Rae Kim, Shine Young Chang, Chulhun L Shin, Ho-Jin Kim, Kye-Hyung Yi, Jongyoun
spellingShingle	Koh, Young Rae Kim, Shine Young Chang, Chulhun L Shin, Ho-Jin Kim, Kye-Hyung Yi, Jongyoun The First Korean Case of Sphingobacterium spiritivorum Bacteremia in a Patient with Acute Myeloid Leukemia
author_facet	Koh, Young Rae Kim, Shine Young Chang, Chulhun L Shin, Ho-Jin Kim, Kye-Hyung Yi, Jongyoun
author_sort	Koh, Young Rae
title	The First Korean Case of Sphingobacterium spiritivorum Bacteremia in a Patient with Acute Myeloid Leukemia
title_short	The First Korean Case of Sphingobacterium spiritivorum Bacteremia in a Patient with Acute Myeloid Leukemia
title_full	The First Korean Case of Sphingobacterium spiritivorum Bacteremia in a Patient with Acute Myeloid Leukemia
title_fullStr	The First Korean Case of Sphingobacterium spiritivorum Bacteremia in a Patient with Acute Myeloid Leukemia
title_full_unstemmed	The First Korean Case of Sphingobacterium spiritivorum Bacteremia in a Patient with Acute Myeloid Leukemia
title_sort	first korean case of sphingobacterium spiritivorum bacteremia in a patient with acute myeloid leukemia
description	Sphingobacterium spiritivorum has been rarely isolated from clinical specimens of immunocompromised patients, and there have been no case reports of S. spiritivorum infection in Korea to our knowledge. We report a case of S. spiritivorum bacteremia in a 68-yr-old woman, who was diagnosed with acute myeloid leukemia and subsequently received chemotherapy. One day after chemotherapy ended, her body temperature increased to 38.3℃. A gram-negative bacillus was isolated in aerobic blood cultures and identified as S. spiritivorum by an automated biochemical system. A 16S rRNA sequencing analysis confirmed that the isolate was S. spiritivorum. The patient received antibiotic therapy for 11 days but died of septic shock. This is the first reported case of human S. spiritivorum infection in Korea. Although human infection is rare, S. spiritivorum can be a fatal opportunistic pathogen in immunocompromised patients.
publisher	The Korean Society for Laboratory Medicine
publishDate	2013
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698308/
_version_	1611990931228065792

The First Korean Case of Sphingobacterium spiritivorum Bacteremia in a Patient with Acute Myeloid Leukemia

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