Hsp70 Oligomerization Is Mediated by an Interaction between the Interdomain Linker and the Substrate-Binding Domain

Oligomerization in the heat shock protein (Hsp) 70 family has been extensively documented both in vitro and in vivo, although the mechanism, the identity of the specific protein regions involved and the physiological relevance of this process are still unclear. We have studied the oligomeric propert...

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Bibliographic Details
Main Authors: Aprile, Francesco A., Dhulesia, Anne, Stengel, Florian, Roodveldt, Cintia, Benesch, Justin L. P., Tortora, Paolo, Robinson, Carol V., Salvatella, Xavier, Dobson, Christopher M., Cremades, Nunilo
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696110/