ThreaDom: extracting protein domain boundary information from multiple threading alignments

Motivation: Protein domains are subunits that can fold and evolve independently. Identification of domain boundary locations is often the first step in protein folding and function annotations. Most of the current methods deduce domain boundaries by sequence-based analysis, which has low accuracy. T...

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Bibliographic Details
Main Authors: Xue, Zhidong, Xu, Dong, Wang, Yan, Zhang, Yang
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694664/