Ablation of Keratan Sulfate Accelerates Early Phase Pathogenesis of ALS

Biopolymers consist of three major classes, i.e., polynucleotides (DNA, RNA), polypeptides (proteins) and polysaccharides (sugar chains). It is widely accepted that polynucleotides and polypeptides play fundamental roles in the pathogenesis of neurodegenerative diseases. But, sugar chains have been...

Full description

Bibliographic Details
Main Authors: Hirano, Kenichi, Ohgomori, Tomohiro, Kobayashi, Kazuyoshi, Tanaka, Fumiaki, Matsumoto, Tomohiro, Natori, Takamitsu, Matsuyama, Yukihiro, Uchimura, Kenji, Sakamoto, Kazuma, Takeuchi, Hideyuki, Hirakawa, Akihiro, Suzumura, Akio, Sobue, Gen, Ishiguro, Naoki, Imagama, Shiro, Kadomatsu, Kenji
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692529/