The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis

In this study, Prokopenko and colleagues provide novel evidence for causal relationship between adiposity and heart failure and increased liver enzymes using a Mendelian randomization study design.

Bibliographic Details
Main Authors: Fall, Tove, Hägg, Sara, Mägi, Reedik, Ploner, Alexander, Fischer, Krista, Horikoshi, Momoko, Sarin, Antti-Pekka, Thorleifsson, Gudmar, Ladenvall, Claes, Kals, Mart, Kuningas, Maris, Draisma, Harmen H. M., Ried, Janina S., van Zuydam, Natalie R., Huikari, Ville, Mangino, Massimo, Sonestedt, Emily, Benyamin, Beben, Nelson, Christopher P., Rivera, Natalia V., Kristiansson, Kati, Shen, Huei-yi, Havulinna, Aki S., Dehghan, Abbas, Donnelly, Louise A., Kaakinen, Marika, Nuotio, Marja-Liisa, Robertson, Neil, de Bruijn, Renée F. A. G., Ikram, M. Arfan, Amin, Najaf, Balmforth, Anthony J., Braund, Peter S., Doney, Alexander S. F., Döring, Angela, Elliott, Paul, Esko, Tõnu, Franco, Oscar H., Gretarsdottir, Solveig, Hartikainen, Anna-Liisa, Heikkilä, Kauko, Herzig, Karl-Heinz, Holm, Hilma, Hottenga, Jouke Jan, Hyppönen, Elina, Illig, Thomas, Isaacs, Aaron, Isomaa, Bo, Karssen, Lennart C., Kettunen, Johannes, Koenig, Wolfgang, Kuulasmaa, Kari, Laatikainen, Tiina, Laitinen, Jaana, Lindgren, Cecilia, Lyssenko, Valeriya, Läärä, Esa, Rayner, Nigel W., Männistö, Satu, Pouta, Anneli, Rathmann, Wolfgang, Rivadeneira, Fernando, Ruokonen, Aimo, Savolainen, Markku J., Sijbrands, Eric J. G., Small, Kerrin S., Smit, Jan H., Steinthorsdottir, Valgerdur, Syvänen, Ann-Christine, Taanila, Anja, Tobin, Martin D., Uitterlinden, Andre G., Willems, Sara M., Willemsen, Gonneke, Witteman, Jacqueline, Perola, Markus, Evans, Alun, Ferrières, Jean, Virtamo, Jarmo, Kee, Frank, Tregouet, David-Alexandre, Arveiler, Dominique, Amouyel, Philippe, Ferrario, Marco M., Brambilla, Paolo, Hall, Alistair S., Heath, Andrew C., Madden, Pamela A. F., Martin, Nicholas G., Montgomery, Grant W., Whitfield, John B., Jula, Antti, Knekt, Paul, Oostra, Ben, van Duijn, Cornelia M., Penninx, Brenda W. J. H., Davey Smith, George, Kaprio, Jaakko, Samani, Nilesh J., Gieger, Christian, Peters, Annette, Wichmann, H.-Erich, Boomsma, Dorret I., de Geus, Eco J. C., Tuomi, TiinaMaija, Power, Chris, Hammond, Christopher J., Spector, Tim D., Lind, Lars, Orho-Melander, Marju, Palmer, Colin Neil Alexander, Morris, Andrew D., Groop, Leif, Järvelin, Marjo-Riitta, Salomaa, Veikko, Vartiainen, Erkki, Hofman, Albert, Ripatti, Samuli, Metspalu, Andres, Thorsteinsdottir, Unnur, Stefansson, Kari, Pedersen, Nancy L., McCarthy, Mark I., Ingelsson, Erik, Prokopenko, Inga
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692470/