SLE Peripheral Blood B Cell, T Cell and Myeloid Cell Transcriptomes Display Unique Profiles and Each Subset Contributes to the Interferon Signature

SLE Peripheral Blood B Cell, T Cell and Myeloid Cell Transcriptomes Display Unique Profiles and Each Subset Contributes to the Interferon Signature

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that is characterized by defective immune tolerance combined with immune cell hyperactivity resulting in the production of pathogenic autoantibodies. Previous gene expression studies employing whole blood or peripheral blood mononucl...

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Bibliographic Details
Main Authors: Becker, Amy M., Dao, Kathryn H., Han, Bobby Kwanghoon, Kornu, Roger, Lakhanpal, Shuchi, Mobley, Angela B., Li, Quan-Zhen, Lian, Yun, Wu, Tianfu, Reimold, Andreas M., Olsen, Nancy J., Karp, David R., Chowdhury, Fatema Z., Farrar, J. David, Satterthwaite, Anne B., Mohan, Chandra, Lipsky, Peter E., Wakeland, Edward K., Davis, Laurie S.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691135/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691135/

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