Endotoxin Exposure during Sensitization to Blomia tropicalis Allergens Shifts TH2 Immunity Towards a TH17-Mediated Airway Neutrophilic Inflammation: Role of TLR4 and TLR2

Endotoxin Exposure during Sensitization to Blomia tropicalis Allergens Shifts TH2 Immunity Towards a TH17-Mediated Airway Neutrophilic Inflammation: Role of TLR4 and TLR2

Experimental evidence and epidemiological studies indicate that exposure to endotoxin lipopolysaccharide (eLPS) or other TLR agonists prevent asthma. We have previously shown in the OVA-model of asthma that eLPS administration during alum-based allergen sensitization blocked the development of lung...

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Bibliographic Details
Main Authors: Barboza, Renato, Câmara, Niels Olsen Saraiva, Gomes, Eliane, Sá-Nunes, Anderson, Florsheim, Esther, Mirotti, Luciana, Labrada, Alexis, Alcântara-Neves, Neuza Maria, Russo, Momtchilo
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689683/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689683/

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