TLR3, TLR4 and TLRs7–9 Induced Interferons Are Not Impaired in Airway and Blood Cells in Well Controlled Asthma

Defective Rhinovirus induced interferon-β and interferon-λ production has been reported in bronchial epithelial cells from asthmatics but the mechanisms of defective interferon induction in asthma are unknown. Virus infection can induce interferon through Toll like Receptors (TLR)3, TLR7 and TLR8. T...

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Bibliographic Details
Main Authors: Sykes, Annemarie, Edwards, Michael R., Macintyre, Jonathan, del Rosario, Ajerico, Gielen, Vera, Haas, Jennifer, Kon, Onn Min, McHale, Mark, Johnston, Sebastian L.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688823/