Indoleamine 2,3-Dioxygenase 1 (Ido1) Is Involved in the Control of Mouse Caput Epididymis Immune Environment

The epididymis maintains a state of immune tolerance towards spermatozoa while also protecting them and itself against infection and acute inflammation. The immunosuppressive enzyme indoleamine 2,3-dioxygenase 1 (Ido1) participates in this delicate local equilibrium. Using the mouse Ido1−/− model, w...

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Bibliographic Details
Main Authors: Jrad-Lamine, Aicha, Henry-Berger, Joelle, Damon-Soubeyrand, Christelle, Saez, Fabrice, Kocer, Ayhan, Janny, Laurent, Pons-Rejraji, Hanae, Munn, David H., Mellor, Andrew L., Gharbi, Najoua, Cadet, Rémi, Guiton, Rachel, Aitken, Robert J., Drevet, Joël R.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688773/