Solubility Enhancement of a Poorly Water Soluble Drug by Forming Solid Dispersions using Mechanochemical Activation

Solubility Enhancement of a Poorly Water Soluble Drug by Forming Solid Dispersions using Mechanochemical Activation

Mechanochemical activation is a practical cogrinding operation used to obtain a solid dispersion of a poorly water soluble drug through changes in the solid state molecular aggregation of drug-carrier mixtures and the formation of noncovalent interactions (hydrogen bonds) between two crystalline sol...

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Bibliographic Details
Main Authors: Rojas-Oviedo, I., Retchkiman-Corona, B., Quirino-Barreda, C. T., Cárdenas, J., Schabes-Retchkiman, P. S.
Format: Online
Language:English
Published: Medknow Publications & Media Pvt Ltd 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687919/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687919/

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