Two Cases of Hypersexuality Probably Associated with Aripiprazole
Sexual dysfunction is a common side effect in patients treated with antipsychotics but significant differences exist across different compounds. We report hypersexuality symptoms in two female patients with schizophrenia who were receiving treatment with aripiprazole. The patients experienced more f...
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| Format: | Online |
| Language: | English |
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Korean Neuropsychiatric Association
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687056/ |
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pubmed-3687056 |
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pubmed-36870562013-06-24 Two Cases of Hypersexuality Probably Associated with Aripiprazole Cheon, EunJin Koo, Bon-Hoon Seo, Sang Soo Lee, Jun-Yeob Case Report Sexual dysfunction is a common side effect in patients treated with antipsychotics but significant differences exist across different compounds. We report hypersexuality symptoms in two female patients with schizophrenia who were receiving treatment with aripiprazole. The patients experienced more frequent sexual desire and greater sexual preoccupation after taking aripiprazole. We discuss the potential neuro-chemical mechanisms for this and argue that aripiprazole's unique pharmacological profile, partial agonism with high affinity at dopamine D2-receptor, may have contributed to the development of these symptoms. Korean Neuropsychiatric Association 2013-06 2013-05-30 /pmc/articles/PMC3687056/ /pubmed/23798970 http://dx.doi.org/10.4306/pi.2013.10.2.200 Text en Copyright © 2013 Korean Neuropsychiatric Association http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Cheon, EunJin Koo, Bon-Hoon Seo, Sang Soo Lee, Jun-Yeob |
| spellingShingle |
Cheon, EunJin Koo, Bon-Hoon Seo, Sang Soo Lee, Jun-Yeob Two Cases of Hypersexuality Probably Associated with Aripiprazole |
| author_facet |
Cheon, EunJin Koo, Bon-Hoon Seo, Sang Soo Lee, Jun-Yeob |
| author_sort |
Cheon, EunJin |
| title |
Two Cases of Hypersexuality Probably Associated with Aripiprazole |
| title_short |
Two Cases of Hypersexuality Probably Associated with Aripiprazole |
| title_full |
Two Cases of Hypersexuality Probably Associated with Aripiprazole |
| title_fullStr |
Two Cases of Hypersexuality Probably Associated with Aripiprazole |
| title_full_unstemmed |
Two Cases of Hypersexuality Probably Associated with Aripiprazole |
| title_sort |
two cases of hypersexuality probably associated with aripiprazole |
| description |
Sexual dysfunction is a common side effect in patients treated with antipsychotics but significant differences exist across different compounds. We report hypersexuality symptoms in two female patients with schizophrenia who were receiving treatment with aripiprazole. The patients experienced more frequent sexual desire and greater sexual preoccupation after taking aripiprazole. We discuss the potential neuro-chemical mechanisms for this and argue that aripiprazole's unique pharmacological profile, partial agonism with high affinity at dopamine D2-receptor, may have contributed to the development of these symptoms. |
| publisher |
Korean Neuropsychiatric Association |
| publishDate |
2013 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687056/ |
| _version_ |
1611987624604467200 |