A Case Report of Malignant Melanoma of the Sphenoid Sinus

Malignant melanoma of the sphenoid sinus is a very rare disease, and only 6 cases have previously been reported. The present case involved a 74-year-old woman who was examined for visual disturbance of the left eye. Computed tomography revealed a soft tissue shadow, but only mucosal hypertrophy was...

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Main Authors: Tsukahara, Kiyoaki, Nakamura, Kazuhiro, Motohashi, Ray, Endo, Minoru, Sato, Hiroki
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686065/
id pubmed-3686065
recordtype oai_dc
spelling pubmed-36860652013-07-16 A Case Report of Malignant Melanoma of the Sphenoid Sinus Tsukahara, Kiyoaki Nakamura, Kazuhiro Motohashi, Ray Endo, Minoru Sato, Hiroki Case Report Malignant melanoma of the sphenoid sinus is a very rare disease, and only 6 cases have previously been reported. The present case involved a 74-year-old woman who was examined for visual disturbance of the left eye. Computed tomography revealed a soft tissue shadow, but only mucosal hypertrophy was found on opening the sphenoid sinus under general anesthesia. One month postoperatively, visual disturbance of the right eye and paresis of cranial nerve III appeared. Malignant melanoma was diagnosed from biopsy. Multiple bone metastases were identified, but the patient declined active treatment. As a result, palliative care was provided and she died 3 months later. When there is no improvement in postoperative visual acuity as in this case, in consideration of the possibility of neoplastic lesions, rigorous followup including monitoring for neurological symptoms is warranted. Hindawi Publishing Corporation 2013 2013-06-03 /pmc/articles/PMC3686065/ /pubmed/23862087 http://dx.doi.org/10.1155/2013/613472 Text en Copyright © 2013 Kiyoaki Tsukahara et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Tsukahara, Kiyoaki
Nakamura, Kazuhiro
Motohashi, Ray
Endo, Minoru
Sato, Hiroki
spellingShingle Tsukahara, Kiyoaki
Nakamura, Kazuhiro
Motohashi, Ray
Endo, Minoru
Sato, Hiroki
A Case Report of Malignant Melanoma of the Sphenoid Sinus
author_facet Tsukahara, Kiyoaki
Nakamura, Kazuhiro
Motohashi, Ray
Endo, Minoru
Sato, Hiroki
author_sort Tsukahara, Kiyoaki
title A Case Report of Malignant Melanoma of the Sphenoid Sinus
title_short A Case Report of Malignant Melanoma of the Sphenoid Sinus
title_full A Case Report of Malignant Melanoma of the Sphenoid Sinus
title_fullStr A Case Report of Malignant Melanoma of the Sphenoid Sinus
title_full_unstemmed A Case Report of Malignant Melanoma of the Sphenoid Sinus
title_sort case report of malignant melanoma of the sphenoid sinus
description Malignant melanoma of the sphenoid sinus is a very rare disease, and only 6 cases have previously been reported. The present case involved a 74-year-old woman who was examined for visual disturbance of the left eye. Computed tomography revealed a soft tissue shadow, but only mucosal hypertrophy was found on opening the sphenoid sinus under general anesthesia. One month postoperatively, visual disturbance of the right eye and paresis of cranial nerve III appeared. Malignant melanoma was diagnosed from biopsy. Multiple bone metastases were identified, but the patient declined active treatment. As a result, palliative care was provided and she died 3 months later. When there is no improvement in postoperative visual acuity as in this case, in consideration of the possibility of neoplastic lesions, rigorous followup including monitoring for neurological symptoms is warranted.
publisher Hindawi Publishing Corporation
publishDate 2013
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686065/
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