Identification of pVHL as a Novel Substrate for Aurora-A in Clear Cell Renal Cell Carcinoma (ccRCC)

Clear cell renal cell carcinoma (ccRCC) is the most common histological subtype of kidney cancer and is often characterized by mutations or deletions of the Von Hippel Lindau (VHL) tumour suppressor gene. Aurora gene family members are implicated in proper mitotic progression and spindle checkpoint...

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Main Authors: Martin, Benedicte, Chesnel, Franck, Delcros, Jean-Guy, Jouan, Florence, Couturier, Anne, Dugay, Frederic, Le Goff, Xavier, Patard, Jean-Jacques, Fergelot, Patricia, Vigneau, Cecile, Rioux-Leclerq, Nathalie, Arlot-Bonnemains, Yannick
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681765/