Nebulin binding impedes mutant desmin filament assembly

Although a clear picture of the in vitro assembly process is established for vimentin, the role of associated partner proteins and their effect on intermediate filament assembly has not been fully examined. This study finds delayed dynamics of desminopathy-linked mutant desmin in myocytes and hinder...

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Main Authors:	Baker, Laura K., Gillis, David C., Sharma, Sarika, Ambrus, Andy, Herrmann, Harald, Conover, Gloria M.
Format:	Online
Language:	English
Published:	The American Society for Cell Biology 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681697/

id	pubmed-3681697
recordtype	oai_dc
spelling	pubmed-36816972013-08-30 Nebulin binding impedes mutant desmin filament assembly Baker, Laura K. Gillis, David C. Sharma, Sarika Ambrus, Andy Herrmann, Harald Conover, Gloria M. Articles Although a clear picture of the in vitro assembly process is established for vimentin, the role of associated partner proteins and their effect on intermediate filament assembly has not been fully examined. This study finds delayed dynamics of desminopathy-linked mutant desmin in myocytes and hindered assembly when associated to nebulin. The American Society for Cell Biology 2013-06-15 /pmc/articles/PMC3681697/ /pubmed/23615443 http://dx.doi.org/10.1091/mbc.E12-11-0840 Text en © 2013 Baker et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0). “ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society of Cell Biology.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Baker, Laura K. Gillis, David C. Sharma, Sarika Ambrus, Andy Herrmann, Harald Conover, Gloria M.
spellingShingle	Baker, Laura K. Gillis, David C. Sharma, Sarika Ambrus, Andy Herrmann, Harald Conover, Gloria M. Nebulin binding impedes mutant desmin filament assembly
author_facet	Baker, Laura K. Gillis, David C. Sharma, Sarika Ambrus, Andy Herrmann, Harald Conover, Gloria M.
author_sort	Baker, Laura K.
title	Nebulin binding impedes mutant desmin filament assembly
title_short	Nebulin binding impedes mutant desmin filament assembly
title_full	Nebulin binding impedes mutant desmin filament assembly
title_fullStr	Nebulin binding impedes mutant desmin filament assembly
title_full_unstemmed	Nebulin binding impedes mutant desmin filament assembly
title_sort	nebulin binding impedes mutant desmin filament assembly
description	Although a clear picture of the in vitro assembly process is established for vimentin, the role of associated partner proteins and their effect on intermediate filament assembly has not been fully examined. This study finds delayed dynamics of desminopathy-linked mutant desmin in myocytes and hindered assembly when associated to nebulin.
publisher	The American Society for Cell Biology
publishDate	2013
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681697/
_version_	1611986309126029312

Nebulin binding impedes mutant desmin filament assembly

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