Crucial function of vertebrate glutaredoxin 3 (PICOT) in iron homeostasis and hemoglobin maturation

Crucial function of vertebrate glutaredoxin 3 (PICOT) in iron homeostasis and hemoglobin maturation

Vertebrate glutaredoxin 3 (PICOT) is essential for the maturation of the heme cofactor of hemoglobin through its essential functions in iron homeostasis. The data suggest an evolutionarily conserved role of cytosolic monothiol multidomain Grxs in cellular iron metabolism pathways.

Bibliographic Details
Main Authors: Haunhorst, Petra, Hanschmann, Eva-Maria, Bräutigam, Lars, Stehling, Oliver, Hoffmann, Bastian, Mühlenhoff, Ulrich, Lill, Roland, Berndt, Carsten, Lillig, Christopher Horst
Format: Online
Language:English
Published: The American Society for Cell Biology 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681695/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681695/

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