Disorders caused by chromosome abnormalities
Many human genetic disorders result from unbalanced chromosome abnormalities, in which there is a net gain or loss of genetic material. Such imbalances often disrupt large numbers of dosage-sensitive, developmentally important genes and result in specific and complex phenotypes. Alternately, some ch...
| Main Authors: | , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Dove Medical Press
2010
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681172/ |