Phosphodiesterase 4 Inhibition in the Treatment of Psoriasis, Psoriatic Arthritis and Other Chronic Inflammatory Diseases

Agents which increase intracellular cyclic adenosine monophosphate (cAMP) may have an antagonistic effect on pro-inflammatory molecule production so that inhibitors of the cAMP degrading phosphodiesterases have been identified as promising drugs in chronic inflammatory disorders. Although many such...

Full description

Bibliographic Details
Main Authors: Wittmann, Miriam, Helliwell, Philip S.
Format: Online
Language:English
Published: Springer Healthcare 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680635/