Activity Determinants of Helical Antimicrobial Peptides: A Large-Scale Computational Study

Antimicrobial peptides (AMPs), produced by a wide range of organisms, have attracted attention due to their potential use as novel antibiotics. The majority of these peptides are cationic and are thought to function by permeabilizing the bacterial membrane, either by making pores or by dissolving it...

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Bibliographic Details
Main Authors: He, Yi, Lazaridis, Themis
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680375/