Coverage Bias and Sensitivity of Variant Calling for Four Whole-genome Sequencing Technologies

The emergence of high-throughput, next-generation sequencing technologies has dramatically altered the way we assess genomes in population genetics and in cancer genomics. Currently, there are four commonly used whole-genome sequencing platforms on the market: Illumina’s HiSeq2000, Life Technologies...

Full description

Bibliographic Details
Main Authors: Rieber, Nora, Zapatka, Marc, Lasitschka, Bärbel, Jones, David, Northcott, Paul, Hutter, Barbara, Jäger, Natalie, Kool, Marcel, Taylor, Michael, Lichter, Peter, Pfister, Stefan, Wolf, Stephan, Brors, Benedikt, Eils, Roland
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679043/