Mefloquine exerts anticancer activity in prostate cancer cells via ROS-mediated modulation of Akt, ERK, JNK and AMPK signaling

Mefloquine exerts anticancer activity in prostate cancer cells via ROS-mediated modulation of Akt, ERK, JNK and AMPK signaling

Mefloquine (MQ) is a prophylactic anti-malarial drug. Previous studies have shown that MQ induces oxidative stress in vitro. Evidence indicates that reactive oxygen species (ROS) may be used as a therapeutic modality to kill cancer cells. This study investigated whether MQ also inhibits prostate can...

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Bibliographic Details
Main Authors: YAN, KUN-HUANG, YAO, CHIH-JUNG, HSIAO, CHI-HAO, LIN, KE-HSUN, LIN, YUNG-WEI, WEN, YU-CHING, LIU, CHUNG-CHI, YAN, MING-DE, CHUANG, SHUANG-EN, LAI, GI-MING, LEE, LIANG-MING
Format: Online
Language:English
Published: D.A. Spandidos 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678889/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678889/

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