Possible Involvement of Foxp3+ Regulatory T Cells in the Development of Immune-Mediated Pancreatitis in MRL/Mp Mice Treated with Polyinosinic:Polycytidylic Acid

Objectives. This study was conducted to clarify whether or not Tregs are involved in the development of immune-mediated pancreatitis in MRL/Mp mice as an AIP (autoimmune pancreatitis) model, in order to understand more clearly the pathogenic mechanism of AIP. Methods. We compared the immunohistoche...

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Bibliographic Details
Main Authors: Koyabu, Masanori, Uchida, Kazushige, Sakaguchi, Yutaku, Fukata, Norimasa, Kusuda, Takeo, Miyoshi, Hideaki, Yoshida, Katsunori, Sumimoto, Kimi, Mitsuyama, Toshiyuki, Fukui, Toshiro, Nishio, Akiyoshi, Okazaki, Kazuichi
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678441/