Transcription of N- and O-linked mannosyltransferase genes is modulated by the pacC gene in the human dermatophyte Trichophyton rubrum

In fungi, ambient pH sensing involves the activation of the Pal/PacC signalling pathway. In the dermatophyte Trichophyton rubrum, pH-dependent secretion of keratinases, which are major virulence determinants, is affected by disruption of the pacC gene. Here, the transcription profiling of the genes...

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Bibliographic Details
Main Authors: Mendes, Niege S., Trevisan, Glauce L., Silva Cruz, Aline H., Santos, Rodrigo S., Peres, Nalu T.A., Martinez-Rossi, Nilce M., Rossi, Antonio
Format: Online
Language:English
Published: Elsevier 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678131/