A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice

A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice

•G protein-coupled receptor 55 (GPR55) is a binding site for cannabinoids.•No conclusive information was available on function of GPR55 in the GI tract.•We found that targeting GPR55 at peripheral or central sites slows GI motility.•Slowing effect of GPR55 activation on GI motility is primarily obse...

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Bibliographic Details
Main Authors: Li, Kun, Fichna, Jakub, Schicho, Rudolf, Saur, Dieter, Bashashati, Mohammad, Mackie, Ken, Li, Yongyu, Zimmer, Andreas, Göke, Burkhard, Sharkey, Keith A., Storr, Martin
Format: Online
Language:English
Published: Pergamon Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677091/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677091/

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