Ultrasound Targeted Microbubble Destruction Stimulates Cellular Endocytosis in Facilitation of Adeno-Associated Virus Delivery
The generally accepted mechanism for ultrasound targeted microbubble destruction (UTMD) to enhance drug and gene delivery is through sonoporation. However, passive uptake of adeno-associated virus (AAV) into cells following sonoporation does not adequately explain observations of enhanced transducti...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
Molecular Diversity Preservation International (MDPI)
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676809/ |