De novo piRNA cluster formation in the Drosophila germ line triggered by transgenes containing a transcribed transposon fragment
PIWI-interacting RNAs (piRNAs) provide defence against transposable element (TE) expansion in the germ line of metazoans. piRNAs are processed from the transcripts encoded by specialized heterochromatic clusters enriched in damaged copies of transposons. How these regions are recognized as a source...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675497/ |