De novo piRNA cluster formation in the Drosophila germ line triggered by transgenes containing a transcribed transposon fragment

PIWI-interacting RNAs (piRNAs) provide defence against transposable element (TE) expansion in the germ line of metazoans. piRNAs are processed from the transcripts encoded by specialized heterochromatic clusters enriched in damaged copies of transposons. How these regions are recognized as a source...

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Bibliographic Details
Main Authors: Olovnikov, Ivan, Ryazansky, Sergei, Shpiz, Sergey, Lavrov, Sergey, Abramov, Yuri, Vaury, Chantal, Jensen, Silke, Kalmykova, Alla
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675497/