Increased Long Chain acyl-Coa Synthetase Activity and Fatty Acid Import Is Linked to Membrane Synthesis for Development of Picornavirus Replication Organelles

Increased Long Chain acyl-Coa Synthetase Activity and Fatty Acid Import Is Linked to Membrane Synthesis for Development of Picornavirus Replication Organelles

All positive strand (+RNA) viruses of eukaryotes replicate their genomes in association with membranes. The mechanisms of membrane remodeling in infected cells represent attractive targets for designing future therapeutics, but our understanding of this process is very limited. Elements of autophagy...

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Bibliographic Details
Main Authors: Nchoutmboube, Jules A., Viktorova, Ekaterina G., Scott, Alison J., Ford, Lauren A., Pei, Zhengtong, Watkins, Paul A., Ernst, Robert K., Belov, George A.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675155/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675155/

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