A Simple and Fast Two-Locus Quality Control Test to Detect False Positives Due to Batch Effects in Genome-Wide Association Studies

A Simple and Fast Two-Locus Quality Control Test to Detect False Positives Due to Batch Effects in Genome-Wide Association Studies

The impact of erroneous genotypes having passed standard quality control (QC) can be severe in genome-wide association studies, genotype imputation, and estimation of heritability and prediction of genetic risk based on single nucleotide polymorphisms (SNP). To detect such genotyping errors, a simpl...

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Bibliographic Details
Main Authors: Lee, Sang Hong, Nyholt, Dale R, Macgregor, Stuart, Henders, Anjali K, Zondervan, Krina T, Montgomery, Grant W, Visscher, Peter M
Format: Online
Language:English
Published: Wiley Subscription Services, Inc., A Wiley Company 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674525/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674525/

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