Modeling cell-in-cell structure into its biological significance
Although cell-in-cell structure was noted 100 years ago, the molecular mechanisms of ‘entering' and the destination of cell-in-cell remain largely unclear. It takes place among the same type of cells (homotypic cell-in-cell) or different types of cells (heterotypic cell-in-cell). Cell-in-cell f...
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| Format: | Online |
| Language: | English |
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Nature Publishing Group
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674356/ |
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pubmed-36743562013-06-06 Modeling cell-in-cell structure into its biological significance He, M-f Wang, S Wang, Y Wang, X-n Review Although cell-in-cell structure was noted 100 years ago, the molecular mechanisms of ‘entering' and the destination of cell-in-cell remain largely unclear. It takes place among the same type of cells (homotypic cell-in-cell) or different types of cells (heterotypic cell-in-cell). Cell-in-cell formation affects both effector cells and their host cells in multiple aspects, while cell-in-cell death is under more intensive investigation. Given that cell-in-cell has an important role in maintaining homeostasis, aberrant cell-in-cell process contributes to the etiopathology in humans. Indeed, cell-in-cell is observed in many pathological processes of human diseases. In this review, we intend to discuss the biological models of cell-in-cell structures under physiological and pathological status. Nature Publishing Group 2013-05 2013-05-16 /pmc/articles/PMC3674356/ /pubmed/23681225 http://dx.doi.org/10.1038/cddis.2013.147 Text en Copyright © 2013 Macmillan Publishers Limited http://creativecommons.org/licenses/by/3.0/ This work is licensed under a Creative Commons Attribution 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/3.0/ |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
He, M-f Wang, S Wang, Y Wang, X-n |
| spellingShingle |
He, M-f Wang, S Wang, Y Wang, X-n Modeling cell-in-cell structure into its biological significance |
| author_facet |
He, M-f Wang, S Wang, Y Wang, X-n |
| author_sort |
He, M-f |
| title |
Modeling cell-in-cell structure into its biological significance |
| title_short |
Modeling cell-in-cell structure into its biological significance |
| title_full |
Modeling cell-in-cell structure into its biological significance |
| title_fullStr |
Modeling cell-in-cell structure into its biological significance |
| title_full_unstemmed |
Modeling cell-in-cell structure into its biological significance |
| title_sort |
modeling cell-in-cell structure into its biological significance |
| description |
Although cell-in-cell structure was noted 100 years ago, the molecular mechanisms of ‘entering' and the destination of cell-in-cell remain largely unclear. It takes place among the same type of cells (homotypic cell-in-cell) or different types of cells (heterotypic cell-in-cell). Cell-in-cell formation affects both effector cells and their host cells in multiple aspects, while cell-in-cell death is under more intensive investigation. Given that cell-in-cell has an important role in maintaining homeostasis, aberrant cell-in-cell process contributes to the etiopathology in humans. Indeed, cell-in-cell is observed in many pathological processes of human diseases. In this review, we intend to discuss the biological models of cell-in-cell structures under physiological and pathological status. |
| publisher |
Nature Publishing Group |
| publishDate |
2013 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674356/ |
| _version_ |
1611984190594613248 |