Importin-7 Mediates Nuclear Trafficking of DNA in Mammalian Cells

Eukaryotic cells have the ability to uptake and transport endogenous and exogenous DNA in their nuclei, however little is known about the specific pathways involved. Here we show that the nuclear transport receptor importin 7 (imp7) supports nuclear import of supercoiled plasmid DNA and human mitoch...

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Bibliographic Details
Main Authors: Dhanoya, Arjun, Wang, Tse, Keshavarz-Moore, Eli, Fassati, Ariberto, Chain, Benjamin M
Format: Online
Language:English
Published: John Wiley & Sons A/S 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672689/