High-Mobility Group Box-1 Induces Decreased Brain-Derived Neurotrophic Factor-Mediated Neuroprotection in the Diabetic Retina

To test the hypothesis that brain-derived neurotrophic factor-(BDNF-) mediated neuroprotection is reduced by high-mobility group box-1 (HMGB1) in diabetic retina, paired vitreous and serum samples from 46 proliferative diabetic retinopathy and 34 nondiabetic patients were assayed for BDNF, HMGB1, so...

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Bibliographic Details
Main Authors: Abu El-Asrar, Ahmed M., Nawaz, Mohd Imtiaz, Siddiquei, Mohammad Mairaj, Al-Kharashi, Abdullah S., Kangave, Dustan, Mohammad, Ghulam
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671668/