RANKL Cytokine: From Pioneer of the Osteoimmunology Era to Cure for a Rare Disease

RANKL Cytokine: From Pioneer of the Osteoimmunology Era to Cure for a Rare Disease

Since its identification, the RANKL cytokine has been demonstrated to play a crucial role in bone homeostasis and lymphoid tissue organization. Genetic defects impairing its function lead to a peculiar form of autosomal recessive osteopetrosis (ARO), a rare genetic bone disease presenting early in l...

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Bibliographic Details
Main Authors: Lo Iacono, Nadia, Pangrazio, Alessandra, Abinun, Mario, Bredius, Robbert, Zecca, Marco, Blair, Harry C., Vezzoni, Paolo, Villa, Anna, Sobacchi, Cristina
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671266/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671266/

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