Sequencing of Candidate Chromosome Instability Genes in Endometrial Cancers Reveals Somatic Mutations in ESCO1, CHTF18, and MRE11A

Sequencing of Candidate Chromosome Instability Genes in Endometrial Cancers Reveals Somatic Mutations in ESCO1, CHTF18, and MRE11A

Most endometrial cancers can be classified histologically as endometrioid, serous, or clear cell. Non-endometrioid endometrial cancers (NEECs; serous and clear cell) are the most clinically aggressive of the three major histotypes and are characterized by aneuploidy, a feature of chromosome instabil...

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Main Authors: Price, Jessica C., Pollock, Lana M., Rudd, Meghan L., Fogoros, Sarah K., Mohamed, Hassan, Hanigan, Christin L., Le Gallo, Matthieu, Program, NIH Intramural Sequencing Center (NISC) Comparative Sequencing, Zhang, Suiyuan, Cruz, Pedro, Cherukuri, Praveen F., Hansen, Nancy F., McManus, Kirk J., Godwin, Andrew K., Sgroi, Dennis C., Mullikin, James C., Merino, Maria J., Hieter, Philip, Bell, Daphne W.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670891/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670891/

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