Scanning a DNA Molecule for Bound Proteins Using Hybrid Magnetic and Optical Tweezers

Scanning a DNA Molecule for Bound Proteins Using Hybrid Magnetic and Optical Tweezers

The functional state of the genome is determined by its interactions with proteins that bind, modify, and move along the DNA. To determine the positions and binding strength of proteins localized on DNA we have developed a combined magnetic and optical tweezers apparatus that allows for both sensiti...

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Bibliographic Details
Main Authors: van Loenhout, Marijn T. J., De Vlaminck, Iwijn, Flebus, Benedetta, den Blanken, Johan F., Zweifel, Ludovit P., Hooning, Koen M., Kerssemakers, Jacob W. J., Dekker, Cees
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670887/

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