Stronger T Cell Immunogenicity of Ovalbumin Expressed Intracellularly in Gram-Negative than in Gram-Positive Bacteria

This study aimed to clarify whether Gram-positive (G+) and Gram-negative (G−) bacteria affect antigen-presenting cells differently and thereby influence the immunogenicity of proteins they express. Lactobacilli, lactococci and Escherichia coli strains were transformed with plasmids conferring intrac...

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Bibliographic Details
Main Authors: Martner, Anna, Östman, Sofia, Lundin, Samuel, Rask, Carola, Björnsson, Viktor, Telemo, Esbjörn, Collins, L. Vincent, Axelsson, Lars, Wold, Agnes E.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669294/