Galectin-9 Activates and Expands Human T-Helper 1 Cells

Galectin-9 (Gal-9) is known for induction of apoptosis in IFN-γ and IL-17 producing T-cells and amelioration of autoimmunity in murine models. On the other hand, Gal-9 induced IFN-γ positive T-cells in a sarcoma mouse model and in food allergy, suggesting that Gal-9 can have diametric effects on T-c...

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Bibliographic Details
Main Authors: Gooden, Marloes J. M., Wiersma, Valerie R., Samplonius, Douwe F., Gerssen, Jurjen, van Ginkel, Robert J., Nijman, Hans W., Hirashima, Mitsuomi, Niki, Toshiro, Eggleton, Paul, Helfrich, Wijnand, Bremer, Edwin
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669208/