Thwarting galectin-induced immunosuppression in breast cancer

Novel therapeutic strategies are needed to counteract breast cancer-associated immunosuppression. Silencing the expression of galectin-1 in a breast carcinoma model inhibited tumor growth and prevented lung metastasis by reducing the frequency and immunosuppressive activity of CD4+CD25+ FOXP3+ regul...

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Bibliographic Details
Main Authors: Salatino, Mariana, Dalotto-Moreno, Tomas, Rabinovich, Gabriel A.
Format: Online
Language:English
Published: Landes Bioscience 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667902/